Faculty Rehan Zafar Paracha

Dr. Rehan Zafar Paracha

Associate Professor
  • Research Centre for Modelling & Simulation
  • 05190855730
  • Doctoral
Summary

Academic Background
Doctorate (VIROLOGY AND IMMUNOLOGY) Doctoral National University of Sciences and Technology September 02, 2009 - October 01, 2015
Master Of Philiosophy (PHARMACEUTICAL CHEMISTRY) Masters Gomal University April 22, 2006 - April 22, 2008
Bachelor of Pharmacy (B.PHARMACY) Bachelor Bahauddin Zakariya University, Multan September 01, 2009 - December 01, 2003
HSSC (PREMEDICAL) Intermediate Federal Board of Intermediate and Secondary Education, Islamabad January 01, 1996 - January 01, 1998
SSC (SCIENCE GROUP) Matric Federal Board of Intermediate and Secondary Education, Islamabad January 01, 1994 - January 01, 1996
Honours and Awards
HEC Best Research Paper HEC Best Research Paper Award, 2014-2015
Research Senior Research Officer Faculty of Pharmacy, Gomal University, D.I Khan. February 08, 2008 - September 30, 2009.
Publications
Evaluating the cleavage efficacy of CRISPR-Cas9 sgRNAs targeting ineffective regions of Arabidopsis thaliana genome May 21, 2021 Afsheen Malik, Alvina Gul, Faiza Munir, Rabia Amir, Hadi Alipour, Mustafeez Mujtaba Babar , Syeda Marriam Bakhtiar, Rehan Zafar Paracha, Zoya Khalid, Muhammad Qasim Hayat PeerJ - Volume 9, e11409
Classification and Computational Analysis of Arabidopsis thaliana Sperm Cell-Specific F-Box Protein Gene 3p.AtFBP113 December 14, 2020 Afsheen Malik, Alvina Gul, Rabia Amir, Faiza Munir, Mustafeez Mujtaba Babar, Syeda Marriam Bakhtiar, Muhammad Qasim Hayat, Rehan Zafar Paracha, Zoya Khalid, Hadi Alipour Frontiers in Genetics - Volume 11, Article Number 609668
New Insight Into Catalytic Mechanism of Glucose-6-Phosphate Dehydrogenase Enzyme: A DFT Study November 02, 2020 Sadaf Rani, Fouzia Perveen, Jerry P Jasinski, Rehan Zafar Paracha, Haris Bin Tanveer, Farooq Ahmad Kiani, Rodrigo Albuquerque Journal of Computational Biophysics and Chemistry - Pages 1-11
Synthesis, crystal structure and DNA binding interactions of ethyl 2-(2-acetamidothiazol-4-yl) acetate: Theoretical and experimental investigations December 15, 2019 Rehan Zafar Paracha, Zafar Iqbal, Zaman Ashraf, Mujahid Abas, Erum Jabeen, Muhammad Nawaz Tahir, Maryum Nisar , Safeer Ahmad Journal of Molecular Structure - Volume: 1198, Article Number: UNSP 126903
Designing, synthesis and characterization of 2-aminothiazole-4-carboxylate Schiff bases; antimicrobial evaluation against multidrug resistant strains and molecular docking September 14, 2019 Saima Ejaz, Humaira Nadeem, Rehan Zafar Paracha, Sadia Sarwar, Sadaf Ejaz BMC Chemistry - Volume: 13, Issue: 1, Article Number: UNSP 115
Systems-Level Understanding of Single-Cell Omics July 11, 2019 Anam Naz, Ayesha Obaid, Aqsa Ikram, Faryal Mehwish Awan, Maryum Nisar, Rehan Zafar Paracha, Amjad Ali Book on Single-Cell Omics - Chapter 20, Volume 1 (Technological Advances), Pages 433-456
Systems-level approaches in Single Cell Omics July 11, 2019 Anam Naz, Ayesha Obaid, Aqsa Ikram, Faryal Mehwish Awan, Maryum Nisar, Rehan Zafar Paracha, Amjad Ali Book on Single-Cell Omics - Volume 1, Chapter 20, Pages 433-456
The Route to 'Chemobrain' - Computational probing of neuronal LTP pathway July 03, 2019 Ammad Fahim, Muhammad Faraz Bhatti, Nasar um Minullah Virk, Rehan Zafar Paracha, Zaira Rehman, Amjad Ali, Amir Rashid Nature Scientific Reports - Volume 9, Article Number 9630
A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia April 04, 2019 Rehan Zafar Paracha, Syed Aun Muhammad, Nighat Fatima, Amjad Ali, Jake Y. Chen Journal of Biological Research-Thessaloniki - Volume 26, Article Number 2
MicroRNAs and their target mRNAs as Potential Biomarkers among Smokers and Non-Smokers with Lung Adenocarcinoma April 01, 2019 Zamir Hussain, Sumaria Malik, Rehan Zafar Paracha, Maryam Khalid, Maryum Nisar, Amnah Siddiqa, Raheel Nawaz, Amjad Ali, Jamil Ahmad IET Systems Biology - Volume 13, Issue 2, Pages 69–76
Parameter estimation of qualitative biological regulatory networks on high performance computing hardware December 29, 2018 Amjad Ali, Muhammad Tariq Saeed, Jamil Ahmad, Jan Baumbach, Josch Pauling, Aamir Shaf, Rehan Zafar Paracha, Asad Hayat BMC Systems Biology - Volume 12, Article Number 146
Identification of Key Genes and Pathways Involved in Compensatory Pancreatic Beta Cell Hyperplasia During Insulin Resistance. November 15, 2018 Rehan Zafar Paracha, Amnah Siddiqa, Jamil Ahmad, Zurah Bibi, Amjad Ali Advances in Computational Science and Computing - pp 420-427
Parallel Computation on Large-Scale DNA Sequences November 10, 2018 Rehan Zafar Paracha, Abdul Majid, Mukhtaj Khan, Mushtaq Khan, Jamil Ahmad, Maozhen Li Applications of Intelligent Technologies in Healthcare - Pages 55-65
Exploring NS3/4A, NS5A and NS5B proteins to design conserved subunit multi-epitope vaccine against HCV utilizing immunoinformatics approaches October 31, 2018 Aqsa Ikram, Tahreem Zaheer, Faryal Mehwish Awan, Ayesha Obaid, Anam Naz, Rumeza Hanif, Rehan Zafar Paracha, Abdul Khaliq Naveed, Hussnain Ahmed Janjua Scientific Reports - Scientific Reports (2018) 8:16107
Structural insights and characterization of human Npas4 protein June 14, 2018 Ammad Fahim, Zaira Rehman, Muhammad Faraz Bhatti, Rehan Zafar Paracha, Amjad Ali, Nasar Virk, Amir Rashid PeerJ -
Color Atlas of Statistics April 04, 2018 Usman Zafar Paracha, Rehan Zafar Paracha, Milena Popovic Amazon Books - 4 April, 2018
Synthesis, Anti-inflammatory, Antimicrobial Potential and Molecular Docking Studies of 4,5-Disubstituted-1,2,4-Triazole Thioacetate Derivatives January 01, 2018 Rehan Zafar Paracha, Muhammad Nouman Arif, Humaira Nadeem, Arifullah Khan, Imran Khanzada, Fawad Ali Letters in Drug Design & Discovery - Volume 15, Issue 0, Pages 1-11, Year 2018
Impact of orientation of carbohydrate binding modules family 22 and 6 on the catalytic activity of Thermotoga maritima xylanase XynB November 01, 2017 Razia Tajwar, Saher Shahid, Rehan Zafar, Muhammad Waheed Akhtar Enzyme and Microbial Technology -
Synthesis, characterization, anti-ulcer action and molecular docking evaluation of novel benzimidazole-pyrazole hybrids September 02, 2017 Abida Noor, Neelum Gul Qazi, Humaira Nadeem, Arif?ullah Khan, Rehan Zafar Paracha, Fawad Ali, Adil Saeed Chemistry Central Journal -
Structural analysis and insight into Zika virus NS5 mediated interferon inhibition July 15, 2017 Hamza Arshad Dar, Tahreem Zaheer, Rehan Zafar Paracha, Amjad ali Infection, Genetics and Evolution - Volume: 51 Pages: 143-152
Formal modeling of mTOR Associated biological regulatory network reveals novel therapeutic strategy for the treatment of cancer June 13, 2017 Zurah Bibi, Jamil Ahmad, Amnah Siddiqa, Rehan Zafar Paracha , Tariq Saeed, Amjad Ali, Hussnain Ahmed Janjua , Shakir Ullah, Emna Ben Abdallah , Olivier Roux Frontiers in Physiology - Volume: 8, Article Number 416
Identification of drug resistance and immune-driven variations in hepatitis C virus (HCV) NS3/4A, NS5A and NS5B regions reveals a new approach toward personalized medicine January 15, 2017 Aqsa Ikram, Ayesha Obaid, Faryal Mehwish Awan, Rumeza Hanif, Anam Naz, Rehan Zafar Paracha, Amjad Ali, Hussnain Ahmed Janjua Antiviral Research - Volume: 137, Pages: 112-124, Published: JAN 2017
Phenotyping in Precision Medicine January 01, 2017 Rehan Zafar Paracha, Ayesha Obaid, Amjad Ali Book on Progress and Challenges in Precision Medicine - Chapter 3, Pages 55-77
Formal modeling and analysis of the hexosamine biosynthetic pathway: role of O-linked N-acetylglucosamine transferase in oncogenesis and cancer progression September 27, 2016 Rehan Zafar Paracha, Muhammad Tariq Saeed, Jamil Ahmad, Shahzina Kanwal, Andreana N. Holowatyj, Iftikhar A. Sheikh, Aamir Shafi, Amnah Siddiqa, Zurah Bibi, Mukaram Khan, Amjad Ali PeerJ - Volume 4, Article Number e2348
Fusion molecules of heat shock protein HSPX with other antigens of mycobacterium tuberculosis show high potential in serodiagnosis of tuberculosis September 21, 2016 Rehan Zafar Paracha, Madeeha Afzal, Ruqyya Khalid, Sana Khurshid, Imran H. Khan, Muhammad Waheed Akhtar PLoS ONE - Volume 11, Issue 9, Article number e0163349
Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets July 19, 2016 Afreenish Hassan, Anam Naz, Ayesha Obaid, Rehan Zafar Paracha, Kanwal Naz, Faryal Mehwish Awan, Syed Aun Muhmmad, Hussnain Ahmed Janjua, Jamil Ahmad, Amjad Ali BMC Genomics - Volume 17, Article Number 732
Characterization of evolutionary changes in hemagglutinin of influenza H1N1 virus: a computational analysis March 01, 2016 Rehan Zafar Paracha, Zaira Rehman, Uzma Amir, Umer H. K. Niazi, Ammad Fahim Virus Disease - Volume 27, Issue 1, Pages 34-40
Structural characterization of ANGPTL8 (betatrophin) with its interacting partner lipoprotein lipase January 25, 2016 Rehan Zafar Paracha, Amnah Siddiqa, Jamil Ahmad, Amjad Ali, Zurah Bibi , Babar Aslam Computational Biology and Chemistry - Volume 61, Pages 210-220
Helicobucter pylori Virulence Regulatory Network: Insights into the Host-Environment and Pathogen Interactions December 01, 2015 Gul Sanober, Jamil Ahmad, Rehan Zafar Paracha, Anam Niz, Baber Aslam, Ayesha Obaid, Afreenish Hassan, Amjad Ali NUST Journal of Natural Sciences - Volume 3, No. 1, Pages 65-77
Prostratin: An Overview November 01, 2015 Rehan Zafar Paracha, Ghulam Abbas Miana, Muhammad Riaz, Syed Shahzad-ul-Hussan, Usman Zafar Paracha Mini-Reviews In Medicinal Chemistry - Volume 15, Number 13, Pages 1122-1130
Fusion of selected regions of mycobacterial antigens for enhancing sensitivity in serodiagnosis of tuberculosis August 01, 2015 Madeeha Afzal, Sana Khurshid, Ruqyya Khalid, Rehan Zafar Paracha, Imran H. Khan, M. Waheed Akhtar Journal of Microbiological Methods - Volume 115, Pages 104-111
Identification of putative vaccine candidates against Helicobacter pylori exploiting exoproteome and secretome: A reverse vaccinology based approach June 01, 2015 Anam Naz, Faryal Mehwish Awan, Ayesha Obaid, Syed Aun Muhammad, Rehan Zafar Paracha, Jamil Ahmad, Amjad Ali Infection, Genetics and Evolution - Volume 32, Pages 280-291
Modeling and analysis of innate immune responses induced by the host cells against hepatitis C virus infection May 01, 2015 Rehan Zafar Paracha, Ayesha Obaid, Jamil Ahmad, Anam Naz, Faryal Mehwish Awan, Samar Hayat Khan Tareen, Sadia Anjum, Jan Baumbach, Amjad Ali, Abida Raza Integrative Biology - Volume 7, Issue 5, Pages 544-559
Structural modeling and analysis of dengue-mediated inhibition of interferon signaling pathway April 28, 2015 Babar Aslam, Jamil Ahmad, Amjad Ali, Rehan Zafar Paracha, Samar Hayat Khan Tareen, Shah Khusro, Taseer Ahmad, S.A. Muhammad, Umar Niazi, V. Azevedo Genetics and Molecular Research - Volume 14, Issue 2, Pages 4215-4237
On the modelling and analysis of the regulatory network of dengue virus pathogenesis and clearance December 01, 2014 Amjad ali, Babar Aslam, Jamil Ahmad, Rehan Zafar Paracha, Samar Hayat Khan Tareen, Umar Niazi, Tariq Saeed Computational Biology and Chemistry - Volume: 53 Pages: 277-291 Part: B
In-silico analysis of claudin-5 reveals novel putative sites for post-translational modifications: Insights into potential molecular determinants of blood–brain barrier breach during HIV-1 infiltration October 01, 2014 Rehan Zafar Paracha, Faryal Mehwish Awan, Sadia Anjum, Ayesha Obaid, Amjad Ali, Hussnain Ahmed Janjua Infection, Genetics and Evolution - Volume 27, Pages 355-365
Formal Modelling of Toll like Receptor 4 and JAK/STAT Signalling Pathways: Insight into the Roles of SOCS-1, Interferon-β and Proinflammatory Cytokines in Sepsis September 25, 2014 Rehan Zafar Paracha, Jamil Ahmad, Amjad Ali, Riaz Hussain, Umar Niaz, Samar Hayat Khan Tareen, Babar Aslam Plos one - Volume 9, Issue 9, Article Number e108466
In silico study of anti-carcinogenic lysyl oxidase-like 2 inhibitors August 01, 2014 Rehan Zafar Paracha, Syed Aun Muhammad, Amjad Ali, Tariq Ismail, Umair Ilyas, Jamil Ahmad Computational Biology and Chemistry - Volume 51, Pages 71-82
Structural evaluation of BTK and PKC delta mediated phosphorylation of MAL at positions Tyr86 and Tyr106 August 01, 2014 Rehan Zafar Paracha, Amjad Ali, Jamil Ahmad, Riaz Hussain, Umar Niazi, Syed Aun Muhammad Computational Biology and Chemistry - Volume: 51 Pages: 22-35
Influence of positioning of carbohydrate binding module on the activity of endoglucanase CelA of Clostridium thermocellum. October 01, 2012 Rehan Zafar Paracha, Muhammad Sajjad, Imran Mahmood Khan, Sajjad Ahmad, Umar H. K. Niazi, Muhammad Waheed Akhtar Journal of Biotechnology - Volume 161, Issue 3, Pages 206-212
Examining the Efficacy of Sorafenib-a Meta-Analysis. June 02, 2011 Usman Z. Paracha, Rehan Z. Paracha, Waseem Hassan, Ghulam Murtaza ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE - Volume 20, Issue 3, Pages 335-342
Conferences
STRUCTURAL CHARACTERIZATION OF NPAS4-ARNT DIMERIZATION THROUGH COMPUTATIONAL SIMULATION May 28, 2019 - May 28, 2019 Rehan Zafar Paracha, Ammad Fahim, Zaira Rehman, Muhammad Faraz Bhatti, Nasar Virk Proceeding of the International Conference on Bioscience and Biotechnology - Malaysia
Modeling and Analysis of the Signaling Crosstalk of PI3K, AMPK and MAPK with Timed Hybrid Petri Nets Approach July 03, 2017 - July 06, 2017 Rehan Zafar Paracha, Zurah Bibi, Jamil Ahmad, Amnah Siddiqa 2017 17th International Conference on Computational Science and Its Applications (ICCSA) - Italy
Teaching Experience:
Assistant Professor Shifa Tameer-e-Millat University November 04, 2013 - December 31, 2015
Assistant Professor Margalla Institute of Health Sciences June 07, 2010 - November 01, 2013
Professional Experience:
CEO Wilsons Pharmaceuticals June 01, 2004 - August 07, 2005
Production Pharmacist Grays Pharmaceuticals December 10, 2003 - February 10, 2004